Person | Bioinspired Materials NCCR | Université de Fribourg

KLOK Harm-Anton

Professor, Research group KLOK

EPFL Laboratoire des Polymères STI IMX LP - Station 12 CH - 1015 Lausanne Switzerland

Email:	harm-anton.klok@epfl.ch
Website:	https://lp.epfl.ch/

Projects lead

Mechanically responsive nanoparticles

Understanding and exploiting the effect of mechanical stress on nanoparticles in biological media

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Projects team

Mechanically responsive and mechanically adapting polymers

Reducing the activation stress threshold of mechanoresponsive materials

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Mechanoresponsive materials enabled by 3D Printing and high-throughput microfluidics

Mimicking Nature's mechanisms for controlled multimaterial growth

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Novel antiviral supramolecular materials

Developping broad-spectrum, low-toxicity and specific virucidal materials

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Development of cargo carriers

Compartmentalized systems to deliver morphogenetic factors

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Development of controlled delivery systems for organ-on-chip devices

Directing the motion of colloidal shuttles with external stimuli

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Swelling-driven mechanical activation of polymers at interfaces and in the networks

Investigating the weak mechanical forces associated with the swelling processes at polymer interfaces

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Mechanochromic force transducers for biosystems and synthetic hydrogels

Sensing forces at the level of single motor proteins and hydrogel cross-links

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Antiviral Surfaces

Broad-spectrum antiviral coatings for high touch surfaces

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Antimicrobial surfaces

A new approach to antimicrobial surfaces and structural antibiotics

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Publications

Mechanoresponsive micro-and nanoparticles
Metze Friederike K., Klok Harm-Anton
CHIMIA International Journal for Chemistry (2019)

Self-assembly of protein-polymer conjugates for drug delivery
Stevens Corey.A., Kaur Kuljeet, Klok Harm-Anton
Advanced Drug Delivery Reviews (2021)

A minimalistic cyclic ice-binding peptide from phage display
Stevens Corey A., Bachtiger Fabienne, Kong Xu-Dong, Abriata Luciano A., Sosso Gabriele C., Gibson Matthew I., Klok Harm-Anton
Nature Communications (2021)

Cellulose Nanocrystals with Tethered Polymer Chains: Chemically Patchy versus Uniform Decoration
Zoppe Justin O., Dupire Alix Vaimiti Marie, Lachat Théo Gaston Gérard, Lemal Philipp, Rodriguez-Lorenzo Laura, Petri-Fink Alke, Weder Christoph, Klok Harm-Anton
ACS Macro Letters (2017)

Lignin: A Sustainable Antiviral Coating Material
Boarino Alice, Wang Heyun, Olgiati Francesca, Artusio Fiora, Özkan Melis, Bertella Stefania, Razza Nicolò, Cagno Valeria, Luterbacher Jeremy S., Klok Harm-Anton, Stellacci Francesco
ACS Sustainable Chemistry & Engineering (2022)

Supramolecular Polymer Brushes
Metze Friederike K., Klok Harm-Anton
ACS Polymers Au (2023)

Swelling-Activated, Soft Mechanochemistry in Polymer Materials
Metze Friederike Katharina, Sant Sabrina, Meng Zhao, Klok Harm-Anton, Kaur Kuljeet
Langmuir (2023)

Supramolecular Polymer Brushes Grown by Surface‐Initiated Atom Transfer Radical Polymerization from Cucurbit[7]uril‐based Non‐Covalent Initiators
Metze Friederike K., Filipucci Irene, Klok Harm-Anton
Angewandte Chemie International Edition (2023)

Linear, Y- and Ψ-shaped poly(2-(dimethylamino)ethyl methacrylate) and poly(methyl methacrylate) brushes prepared by surface-initiated polymerization from a homologous series of ATRP initiators
Sant Sabrina, Klok Harm-Anton
European Polymer Journal (2023)

Disulfide-Cross-Linked Tetra-PEG Gels
Meng Zhao, Löser Lucas, Saalwächter Kay, Gasser Urs, Klok Harm-Anton
Macromolecules (2024)

KLOK Harm-Anton

Mechanically responsive nanoparticles

Mechanically responsive and mechanically adapting polymers

Mechanoresponsive materials enabled by 3D Printing and high-throughput microfluidics

Novel antiviral supramolecular materials

Development of cargo carriers

Development of controlled delivery systems for organ-on-chip devices

Swelling-driven mechanical activation of polymers at interfaces and in the networks

Mechanochromic force transducers for biosystems and synthetic hydrogels

Antiviral Surfaces

Antimicrobial surfaces