Module 3. Responsive bio-interfaces

Interfaces between living and synthetic materials often determine the fate and function of engineered biological materials. During Phases 1 and 2 (2014-2022), Module 3 focused on developing a range of materials to direct cell growth and tissue differentiation, induce or inhibit specific cell responses, sense biomarkers in complex and diluted environments, and inhibit viral infections, among others. In Phase 3 (2022-2026), Module 3 has become a multidisciplinary research program involving research groups from all former topical modules. Under the common theme of “responsive bio-interfaces”, the current projects seek diverse goals, including the development of scaffolds that enable guided tissue growth, the 3D printing of cm-sized organoids at room temperature, the understanding of the molecular mechanisms promoting or antagonizing dispersion stability of protein systems, the introduction of novel antiviral and antimicrobial surfaces, the design of DNA-Origami-based nanosensors for cancer diagnostics and the development of 2D material-based ion-gradient batteries.