Module 3 (2014-2018): Interactions of responsive materials with cells

Although smart (nano)materials with specific functionalities promise important breakthroughs in diagnosis and therapy, progress of in particular the latter is comparably slow, which is attributed to many factors such as the lack of robustness of the materials and the limited understanding of the fundamental biological interactions. The main goal of Module 3 is thus to improve the fundamental understanding of the interaction of controlled stimuli-responsive materials with biological systems. The acquired know-how and achievements have resulted at the end of the first funding phase in the development of robust smart systems capable of amplifying weak biochemical signals, modifying the stiffness of cell substrates in situ, and targeting and killing of specific cells, e.g. cancer cells.