Person | Bioinspired Materials NCCR | Université de Fribourg

STELLACCI Francesco

Professor, Research group STELLACCI

EPFL STI IMX SUNMIL MXG 030 (Bâtiment MXG) Station 12 CH-1015 Lausanne Switzerland

Email:	francesco.stellacci@epfl.ch
Website:	http://sunmil.epfl.ch/

Projects lead

Novel antiviral supramolecular materials

Developping broad-spectrum, low-toxicity and specific virucidal materials

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Projects team

Characterizing nanoparticle-membrane interactions via molecular dynamics simulations

Investigating how the surface chemistry of nanoparticles dictates their interaction with cells

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Fluorescent nanodiamonds as quantum bio-molecular probes for live cell imaging and sensing

Towards super-resolution imaging in quantum physics and life sciences

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Stimulation of cellular endocytosis for sensing and enhancing nanoparticle uptake

Sensing and enhancing nanoparticle uptake

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Mechano-responsive CaCO3-based coatings

Understanding how the processing conditions of CaCO3 influence the properties of derived composite materials

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Increasing dispersion stability with biocompatible small molecules

Modulating particle aggregation within the cell and in industrial formulations

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Antiviral Surfaces

Broad-spectrum antiviral coatings for high touch surfaces

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Antimicrobial surfaces

A new approach to antimicrobial surfaces and structural antibiotics

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Co-Assembly of Biomolecular Nanocages with Nanoparticles and Proteins to Synthesize Hybrid Functional Material for Biomedical Application

Developing and characterizing protein and DNA-based nanocontainers for encapsulation, transport, and…

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Publications

Broad-spectrum non-toxic antiviral nanoparticles with a virucidal inhibition mechanism
Cagno Valeria, Andreozzi Patrizia, D’Alicarnasso Marco, Jacob Silva Paulo, Mueller Marie, Galloux Marie, Le Goffic Ronan, Jones Samuel T., Vallino Marta, Hodek Jan, Weber Jan, Sen Soumyo, Janeček Emma-Rose, Bekdemir Ahmet, Sanavio Barbara, Martinelli Chiara, Donalisio Manuela, Rameix Welti Marie-Anne, Eleouet Jean-Francois, Han Yanxiao, Kaiser Laurent, Vukovic Lela, Tapparel Caroline, Král Petr, Krol Silke, Lembo David, Stellacci Francesco
Nature Materials (2017)

Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months
Pelliccia Maria, Andreozzi Patrizia, Paulose Jayson, D’Alicarnasso Marco, Cagno Valeria, Donalisio Manuela, Civra Andrea, Broeckel Rebecca M., Haese Nicole, Jacob Silva Paulo, Carney Randy P., Marjomäki Varpu, Streblow Daniel N., Lembo David, Stellacci Francesco, Vitelli Vincenzo, Krol Silke
Nature Communications (2016)

A centrifugation-based physicochemical characterization method for the interaction between proteins and nanoparticles
Bekdemir Ahmet, Stellacci Francesco
Nature Communications (2016)

Amorphous CaCO3: Influence of the formation time on its degree of hydration and stability
Du Huachuan, Steinacher Mathias, Borca Camelia, Huthwelker Thomas, Murello Anna, Stellacci Francesco, Amstad Esther
Journal of the American Chemical Society (2018)

Amphiphilic nanoparticle delivery enhances the anticancer efficacy of a TLR7 ligand via local immune activation
Mottas Inès, Bekdemir Ahmet, Cereghetti Alessandra, Spagnuolo Lorenzo, Yang Yu-Sang Sabrina, Müller Marie, Irvine Darrell J., Stellacci Francesco, Bourquin Carole
Biomaterials (2019)

An atomistic look into bio-inspired nanoparticles and their molecular interactions with cells
Petretto Emanuele, Campomanes Pablo, Stellacci Francesco, Rothen-Rutishauser Barbara, Petri-Fink Alke, Vanni Stefano
CHIMIA International Journal for Chemistry (2019)

Modified cyclodextrins as broad-spectrum antivirals
Jones Samuel T., Cagno Valeria, Janeček Matej, Ortiz Daniel, Gasilova Natalia, Piret Jocelyne, Gasbarri Matteo, Constant David A., Han Yanxiao, Vuković Lela, Král Petr, Kaiser Laurent, Huang Song, Constant Samuel, Kirkegaard Karla, Boivin Guy, Stellacci Francesco, Tapparel Caroline
Science Advances (2020)

SARS-CoV-2 inhibition by sulfonated compounds
Gasbarri Matteo, V’kovski Philip, Torriani Giulia, Thiel Volker, Stellacci Francesco, Tapparel Caroline, Cagno Valeria
Microorganisms (2020)

Quantitative 3D determination of self-assembled structures on nanoparticles using small angle neutron scattering
Luo Zhi, Marson Domenico, Ong Quy K., Loiudice Anna, Kohlbrecher Joachim, Radulescu Aurel, Krause-Heuer Anwen, Darwish Tamim, Balog Sandor, Buonsanti Raffaella, Svergun Dmitri I., Posocco Paola, Stellacci Francesco
Nature Communications (2018)

Reversible microscale assembly of nanoparticles driven by the phase transition of a thermotropic liquid crystal
Fhionnlaoich Niamh Mac, Schrettl Stephen, Tito Nicholas B., Yang Ye, Nair Malavika, Serrano Luis A., Harkness Kellen, Silva Paulo Jacob, Frauenrath Holger, Stellacci Francesco, Guldin Stefan
not found (2018)

Reversible microscale assembly of nanoparticles driven by the phase transition of a thermotropic liquid crystal
Fhionnlaoich Niamh Mac, Schrettl Stephen, Tito Nicholas B., Yang Ye, Nair Malavika, Serrano Luis A., Harkness Kellen, Silva Paulo Jacob, Frauenrath Holger, Stellacci Francesco, Guldin Stefan
not found (2017)

Nature‐inspired circular‐economy recycling for proteins: Proof of concept
Giaveri Simone, Schmitt Adeline Marie, Roset Julià Laura, Scamarcio Vincenzo, Murello Anna, Cheng Shiyu, Menin Laure, Ortiz Daniel, Patiny Luc, Bolisetty Sreenath, Mezzenga Raffaele, Maerkl Sebastian Josef, Stellacci Francesco
Advanced Materials (2021)

Polyanionic Amphiphilic Dendritic Polyglycerols as Broad-Spectrum Viral Inhibitors with a Virucidal Mechanism
Mohammadifar Ehsan, Gasbarri Matteo, Cagno Valeria, Achazi Katharina, Tapparel Caroline, Haag Rainer, Stellacci Francesco
Biomacromolecules (2022)

Potent Virustatic Polymer–Lipid Nanomimics Block Viral Entry and Inhibit Malaria Parasites In Vivo
Najer Adrian, Blight Joshua, Ducker Catherine B., Gasbarri Matteo, Brown Jonathan C., Che Junyi, Høgset Håkon, Saunders Catherine, Ojansivu Miina, Lu Zixuan, Lin Yiyang, Yeow Jonathan, Rifaie-Graham Omar, Potter Michael, Tonkin Renée, Penders Jelle, Doutch James J., Georgiadou Athina, Barriga Hanna M. G., Holme Margaret N., Cunnington Aubrey J., Bugeon Laurence, Dallman Margaret J., Barclay Wendy S., Stellacci Francesco, Baum Jake, Stevens Molly M.
ACS Central Science (2022)

Monovalent ion-mediated charge–charge interactions drive aggregation of surface-functionalized gold nanoparticles
Petretto Emanuele, Ong Quy K., Olgiati Francesca, Mao Ting, Campomanes Pablo, Stellacci Francesco, Vanni Stefano
Nanoscale (2022)

Lignin: A Sustainable Antiviral Coating Material
Boarino Alice, Wang Heyun, Olgiati Francesca, Artusio Fiora, Özkan Melis, Bertella Stefania, Razza Nicolò, Cagno Valeria, Luterbacher Jeremy S., Klok Harm-Anton, Stellacci Francesco
ACS Sustainable Chemistry & Engineering (2022)

STELLACCI Francesco

Novel antiviral supramolecular materials

Characterizing nanoparticle-membrane interactions via molecular dynamics simulations

Fluorescent nanodiamonds as quantum bio-molecular probes for live cell imaging and sensing

Stimulation of cellular endocytosis for sensing and enhancing nanoparticle uptake

Mechano-responsive CaCO3-based coatings

Increasing dispersion stability with biocompatible small molecules

Antiviral Surfaces

Antimicrobial surfaces

Co-Assembly of Biomolecular Nanocages with Nanoparticles and Proteins to Synthesize Hybrid Functional Material for Biomedical Application